Primary Faculty
Alphabetically
Antin, Parker
Molecular Regulation of Vertebrate Development.
Bernstein, Harris
Colon cancer
Bowden, Timothy
Molecular mechanisms of physical and chemical carcinogenesis; cellular oncogene activation and differential gene expression during tumor progression.
Cress, Anne
Cellular adhesion and tumor progression.
Darnell, Dianna
Gallus Expression In Situ Hybridization Analysis
Doetschman, Tom
TGFbeta and FGF2 Gene Function in Mouse Models of Human Disease
Dvorak, Katerina
Cancer Biology, GI cancer, Barrett's esophagus
Elliott, David
Nutrient uptake by Plasmodium falciparum
Gerner, Eugene
Our laboratory investigates the role of genetic and intestinal luminal risk factors in gastrointestinal (GI) carcinogenesis
Gordon, Herman
Research includes using a muscle cell culture model in which we can observe the aggregation of known synaptic molecules in response to neurons or active factors such as neural agrin. There appear to be 2 basic pathways which regulate the aggregation of synaptic molecules: one involves signal transduction and tyrosine phosphorylation while the other may involve structural interactions on the extracellular surface. When observed in detail, the aggregation is quite dynamic in surprising ways that we hope will promote a better understanding of the underlying processes & nbsp; Future research will hope to answer the question of how one synapse gets larger at the expense of the other.
Gregorio, Carol
Identification of the molecular components and signaling mechanisms that regulate cytoskeletal protein interactions during striated muscle development and cardiac muscle disease.
Krieg, Paul
Organogenesis; development of the vertebrate heart and blood vessels.
Lantz, Clark
Pulmonary toxicology
Lybarger, Lonnie
MHC class I antigen presentation
Martinez, Jesse
Function and regulation of the p53 tumor suppressor protein; Role of p53 & 14-3-3 proteins in genomic instability in lung cancer; The role of bile acids in colon cancer etiology.
McCuskey, Robert
Microcirculation; in vivo microscopy; Liver Pathobiology
McDermott, Kimberly
The role of primary cilia in normal mammary gland development and breast cancer progression
McMullen, Nathan
The Neurobiology of Hearing: Dendritic and Axonal Circuits Underlying Frequency Maps in the Auditory Central Nervous System
Nagel, Raymond
Pathogenesis of human cancer
Nolte, John
Professor in Cell Biology and Anatomy
Payne, Claire
Studies of mechanisms of cell death (including apoptosis), molecular and cellular pathology, colon carcinogenesis and in situ molecular imaging techniques.
Restifo, Linda
Genetics of brain development and neuronal plasticity; genetics of mental retardation; drug discovery for neurotherapeutics; Drosophila neurogenetics.
Rogers, Gregory
Regulation of centrosome duplication and function. Assembly of microtubule arrays.
Runyan, Raymond
Mechanisms of tissue interaction and cellular transformation in the developing valves of the heart. Environmental causes of congenital heart disease.
St. John, Paul
Binding and uptake of amyloid-β peptide in CNS neurons. Amyloid-β-induced changes in the function and survival of CNS neurons. Dynamic movements of neurotransmitter receptors in neurons and muscle cells. Self-assembly of amyloid-β peptides. Effects of amyloid-β on the trafficking of AMPA-type glutamate receptors in chemical LTD – an in vitro model of synaptic defects in Alzheimer's disease. Alzheimer's disease.
Tolbert, Leslie
Neuron-neuron and neuron-glia interactions during development; development of olfactory system in insect model
Vercelli, Donata
Research in the Functional Genomics Laboratory focuses on the molecular mechanisms underlying the pathogenesis of human complex diseases, such as asthma and allergy.
Wilson, Jean
Research interests include epithelial cells and neurons and their relation to regulation of development and polarity. Current projects include studying the molecular machinery that regulates the polarized targeting of proteins in epithelial cells.